Innerspace (1987)

120 min - Adventure,Comedy,Sci-Fi
A hapless store clerk must foil criminals to save the life of the man who, miniaturized in a secret experiment, was accidentally injected into him.
Director: Joe Dante
Writers: Chip Proser,Jeffrey Boam
Stars: Dennis Quaid,Martin Short,Meg Ryan
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Avatar was initially planned by James Cameron as a 1999's immediate follow-up to Titanic (produced in 1997). However, the CGI for the film would swell the budget to an overwhelming $400 million. Cameron could not get funding for the film at the time.
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